Revolutionizing Craniomaxillofacial Regeneration: 3D Printing, Bone Tissue Engineering, and AI-Driven Innovations (Ongoing)

Posted On 2025-09-09 15:21:35


This series on Revolutionizing Craniomaxillofacial Regeneration: 3D Printing, Bone Tissue Engineering, and AI-Driven Innovations is co-edited by Dr. Fernando P.S. Guastaldi, from Massachusetts General Hospital, Harvard School of Dental Medicine, USA; Dr. Yannick M. Sillmann, from University Hospital Ulm, Germany; and Dr. Henrique Hadad from Karolinska Institute, Sweden.

Fernando P.S. Guastaldi, DDS, MSc, PhD
Massachusetts General Hospital, Harvard School of Dental Medicine, USA

Fernando P.S. Guastaldi is an Assistant Professor of Oral and Maxillofacial Surgery at Harvard School of Dental Medicine and Director of the Skeletal Biology Research Center at Massachusetts General Hospital. He is a surgeon-scientist-educator focused on understanding, developing, and translating strategies to tissue-engineer vascularized 3D-printed bone scaffolds for the regeneration of large maxillofacial bone defects. His research applies innovative biomaterials, technologies, and approaches to unmet clinical needs in Oral and Maxillofacial Surgery. He also works with animal models for biomedical research, temporomandibular joint (TMJ) osteoarthritis (OA) and regeneration, and artificial intelligence in Oral and Maxillofacial Surgery. He has published several peer-reviewed articles in the fields of bone tissue engineering, TMJ-OA, and TMJ regeneration. He is one of the editors of the book “Bone Tissue Engineering: Bench to Bedside Using 3D Printing” (Springer, 2022).

Yannick M. Sillmann, DDS, MD candidate
University Hospital Ulm, Germany

Yannick M. Sillmann is a board-certified dentist with a strong academic and clinical focus on oral and maxillofacial surgery (OMS). Additionally, he is a final-year medical student at Ulm University and an M.D. candidate at the Department of Oral and Plastic Maxillofacial Surgery.

His research interests center on bone tissue engineering, regenerative medicine, and the integration of digital technologies in surgical practice. As a Research Fellow at the Skeletal Biology Research Center at Massachusetts General Hospital (MGH) and the Harvard School of Dental Medicine, Dr. Sillmann contributes to translational projects in biomaterials, bone regeneration, and craniofacial reconstruction.

Dr. Sillmann’s work emphasizes clinical applications of patient-specific implants, AI-assisted surgical planning, and regenerative approaches to improve outcomes in OMS. Combining expertise in dentistry, medicine, and surgical research, he adopts an interdisciplinary approach to bridge the gap between basic science and clinical innovation.

Henrique Hadad, DDS, MSc, PhD
Karolinska Institute, Sweden

Henrique Hadad is a Postdoctoral Researcher at Karolinska Institutet (KI) in Stockholm, Sweden, in the Department of Women's and Children's Health, working at the Center for Molecular Medicine on Skeletal and Growth Disorders. Dr. Hadad holds an MSc and PhD in Bone Biology, specifically in Oral and Maxillofacial Surgery. He has experience with animal models to address questions in Oral Surgery, working primarily on the following topics: bone healing, biomaterials, dental implants, osseointegration and surface modification, medication-related osteonecrosis of the jaw (MRONJ), temporomandibular disorders (TMD), and cartilage biology.

Series Outline

  1. Biomaterials, tissue engineering
  2. Biomedical engineering
  3. Biomedical engineering, 3D printing in OMS
  4. Artificial intelligence applications and virtual reality in OMS
  5. CBCT segmentation in digital dentistry
  6. Bone regeneration
  7. Bone tissue engineering, craniomaxillofacial regeneration
  8. Bone regeneration, implant dentistry, artificial intelligence
  9. Artificial intelligence applications, bio-materials, implant dentistry

Disclosure:
The series “Revolutionizing Craniomaxillofacial Regeneration: 3D Printing, Bone Tissue Engineering, and AI-Driven Innovations” was commissioned by the editorial office, Frontiers of Oral and Maxillofacial Medicine without any sponsorship or funding. Fernando P.S. Guastaldi, Yannick M. Sillmann and Henrique Hadad are serving as the unpaid Guest Editors for the series.